This book focuses on the DNA viruses in the human population that are associated with cancers. It covers most of the viruses that are thought to contribute to human malignancy. The book represents a comprehensive review of the field of DNA tumor virology.
DNA Tumor Viruses will focus on the DNA viruses in the human population that are associated with cancers.
Inhaltsverzeichnis
Polyomavirus Life Cycle.- Transformation by Polyomaviruses.- Polyomaviruses and Disease.- The Life Cycle of Human Papillomaviruses.- Papillomavirus Transformation.- Papillomaviruses: Biology, Diversity, and Pathogenesis.- Adenovirus Transformation.- Overview of the Large DNA Tumor Viruses.- Epidemiology of EBV Infection.- EBV Diseases.- The Epstein Barr Virus Genome.- Epstein Barr Virus Transforming Proteins: Biologic Properties and Contribution to Oncogenesis.- The Epstein Barr Virus Lytic Life Cycle.- Epstein Barr Virus Latent Infection Nuclear Proteins: Genome Maintenance and Regulation of Lymphocyte Cell Growth and Survival.- Epstein Barr Virus Entry.- EBV Immunotherapy.- KSHV Epidemiology and Subtype Evolution.- to Diseases Associated with Kaposi s Sarcoma-Associated Herpesvirus.- Organization and Expression of the Kaposi s Sarcoma-Associated Herpesvirus Genome.- KSHV Latent Genes and Their Regulation.- Regulation of Expression, Mode of Action and Downstream Targets of ORF50 Protein in KSHV Lytic Cycle Activation.- HHV-8/KSHV Proteins Involved in Signaling and Transformation.- KSHV Entry and Infection of Target Cells.- KSHV Immune Evasion.- Non-coding Regulatory RNAs of the DNA Tumor Viruses.- AIDS and Associated Malignancies.- Primate Models for Gammaherpesvirus-Associated Malignancies.- Murine Gammaherpesvirus 68 Infection of Mice: A Small Animal Model for Characterizing Basic Aspects of Gammaherpesvirus Pathogenesis.